This study examined whether participants in the U.K. Understanding Society Innovation Panel were willing to provide a blood sample in different interview settings (randomly assigned to 1. Nurse collection of dried blood spot (DBS), 2. Nurse collection of blood sample by venepuncture, or 3. Self-collection of DBS), and how resulting cardiovascular risk biomarkers compared. Although the willingness was lowest in the self-collection DBS, demographic characteristics of participants in self-collection mode were not different to those in nurse collection mode. Further, clinical biomarker information relevant to cardiovascular disease risk did not differ between the venepuncture blood sample and the DBS. This demonstrates that DBS collection offers acceptable measures of clinically relevant biomarkers, enabling the calculation of population levels of cardiovascular disease risk.
